
Results from a double-blinded randomised controlled trial involving 26 individuals with Irritable Bowel Syndrome (IBS) who had been following a low FODMAP diet showed that a three week intervention with ur gut® led to improved outcomes in their gut and mental health (1).
The daily serve (40g) of ur gut® also increased dietary fibre intake to levels recommended in the Australian Dietary Guidelines (ADG). (2, 3). Our research has shown that resistant starch intake in people with IBS who were following a low FODMAP diet was below recommended levels (4).
In response, the ECU scientists designed a study to test a new dietary fibre powder with a unique formula and a gradient dosage, whose effects have been identified in the double-blinded randomised controlled trial for four weeks. This study (5) incorporated assessment of diet quality, gut microbiota, mental health, sleep and quality of life.
Twenty six people with IBS were randomly assigned into either the ur gut® group or a placebo group and consumed the corresponding dietary powder for three weeks, after completing a one week baseline observation (5). At the start of the study, participants had good sleep patterns that were not disrupted throughout the trial.
Sleep was measured using a ReadiBand, a sleep capture device that tracks sleep data. Similarly, gut symptom severity was monitored using a validated questionnaire and low to moderate level gut symptoms were maintained (1). ur gut beneficially altered gut microbial composition. ur gut® improved GI-specific anxiety and sexual subscale of quality of life, with overall dietary patterns and quality maintained. Participants in the u r group reported less energy and protein consumption than their baseline levels (1).
ECU scientists want to share this dietary fibre product with more people to support the gut health of the Australian community (6)
1. Yan, R. (2023). Does Fibre-fix provided to people with irritable bowel syndrome who are consuming a low FODMAP diet improve their gut health, gut microbiome, sleep and mental health? Edith Cowan University. https://pubmed.ncbi.nlm.nih.gov/32816830/
2. National Health and Medical Research Council. Australian Government. Nutrient Reference Values for Australia and New Zealand In: Department of Health and Ageing New Zealand Ministry of Health, editor. Canberra: National Health and Medical Research Council; 2006.
3. National Health and Medical Research Council (2013) Australian Dietary Guidelines. Canberra: National Health and Medical Research Council.
4. Yan, R., Devine, A., Marlow, E., Lo, J., Dunican, I., Kunaratnam, K., Andrew, L., & Christophersen, C. (2022). Resistant Starch Intake Is Low in Australian Adults With Irritable Bowel Syndrome Who Follow a Low FODMAP Diet. Current Developments in Nutrition, 6(Supplement_1), 757-757. https://doi.org/10.1093/cdn/nzac062.026
5. Yan, R., Murphy, M., Genoni, A., Marlow, E., Dunican, I. C., Lo, J., Andrew, L., Devine, A., & Christophersen, C. T. (2020). Does Fibre-fix provided to people with irritable bowel syndrome who are consuming a low FODMAP diet improve their gut health, gut microbiome, sleep and mental health? A double-blinded, randomised controlled trial. BMJ Open Gastroenterology, 7(1), e000448. https://doi.org/10.1136/bmjgast-2020-000448
6. Yan, R., Andrew, L., Marlow, E., Kunaratnam, K., Devine, A., Dunican, I. C., & Christophersen, C. T. (2021). Dietary fibre intervention for gut microbiota, sleep and mental health in adults with irritable bowel syndrome: A scoping review. Nutrients, 13(7). https://doi.org/10.3390/nu13072159

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Australian Patent Application 2023902137
PCT/AU2024/050721
